Quantification of Tamoxifen in Pharmaceutical Formulations Using Micellar Liquid Chromatography
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چکیده
منابع مشابه
Quantification of tamoxifen in pharmaceutical formulations using micellar liquid chromatography.
This paper describes a micellar liquid chromatographic method used to analyze tamoxifen (TAMO) in pharmaceutical formulations, while focusing in its interesting features. Solid samples were solved in a micellar solution, irradiated at 254 nm, filtered and injected. Extraction steps were avoided and thus expediting the procedure. Tamoxifen was resolved in <5 min, using a mobile phase containing ...
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Address correspondence to S. Carda Broch. endroflumethiazide (BMFT [RS]-3-phenylmethyl-3,4-dihydro-6-trif luoromethyl-2H1,2,4-benzothiadiazine-7-sulfonamide-1,1dioxide) is a potent diuretic drug extensively used for the treatment of hypertension and oedema that belongs to the thiazide family (1). BMFT is well absorbed from the gastrointestinal tract after oral administration and the absorption ...
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A micellar chromatographic method has been developed and validated for simultaneous separation and determination of metformin(MF), nateglinide (NT) and gliclazide (GL). The separation was carried out using a Nucleosil C18 column, 150 mm × 4.6 mm i.d., 5 μm particle size, using micellar mobile phase consisting of sodium dodecyl sulphate (SDS), n-propanol with UV detection. The optimum conditions...
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ژورنال
عنوان ژورنال: Analytical Sciences
سال: 2014
ISSN: 0910-6340,1348-2246
DOI: 10.2116/analsci.30.925